Genetically Modified Grain

By: Jeri Yoder

For Senior Seminar
Professor Stan Grove

November 15, 1999

Thesis: Genetically Modified Grain has many benefits and problems which have become very controversial. While these problems need to be addressed, the benefits outweigh the drawbacks. GMO grain should be grown and foods containing them should not be required to bare a label.

I. What is GMO Grain?
II. Benefits of GMO Grain
A. Increased Yields
B. Decreased Environment Strain
C. Improve Farmer Economics
D. Health Advantages
III. Problems of GMO Grain
A. Unknown Health Outcome
B. Identity Preservation
C. Terminator Technology
IV. Societal Views
A. Press Responsibility
B. Some Companies won't buy GMO grain
C. Novartis Fights Back
V. Conclusion

 

Introduction

Genetically improved crops are not a new phenomenon. Plants have been selectively crossbred for centuries to develop heartier and more productive hybrids. Now, Biotechnology offers us the ability to transfer desired traits into plants much faster and more selectively by merely transplanting the desired gene into the grain. Genetically Modified Grain (GMO grain) is now available to the public. It has the potential to revolutionize the agriculture industry by giving us the potential to substantially increase yield, lessen the strain on the environment, improve economics for farmers, and help meet incredible demand for food that will come as the population nearly doubles in forthcoming decades (Knutson, 1999). However, GMO grain also has its drawbacks. It has been extensively tested, but ultimately, the long-term health outcome to humans and animals is unknown. GMO grain is highly technical and expensive to research and develop. There is the possibility that larger companies will form a monopoly. Also, there are many ethical issues to consider including the development of terminator technology-a gene inserted into seeds that causes the next generation of seeds to be sterile.

Benefits

One example of a genetically modified seed that is commonly used today is Bt Corn. The Bt gene that is used comes from bacteria-Bacillus thuringiensis (Bt.). It has been used in sprays and powder form for years. Recently, this gene was isolated and successfully incorporated it into the DNA of the corn. The corn then goes on to produce a protein that is deadly to insects, and corn borers specifically. This protein is not toxic to humans; it is broken down in the digestive system. Bt corn does not completely eliminate the need for insecticides, but greatly helps.

In 1997, 4.5 million acres were planted to Bt. hybrids (Beeler, 1998). Today, 30 to 40% of corn and 50% of soybeans are GMO crops (Hein, 1999). This is quite a substantial percentage of our crops considering that many consider the existence of GMO crops to still be controversial. More than thirty genetically engineered plants are permitted for sale by law world wide (Hein, 1999).

Knutson, Texas A&M professor, estimates that we will not be able to feed the global population in the next 50 years unless we continue to increase crop production. In fact, we must triple farm output over the next 50 years to meet growing demands for food (American...1999). Biotechnology offers farmers capability to significantly increase yields without sacrificing huge tracts of forests and wetlands to low-yield crops and pasture.

We can not significantly increase yields without the helping hand of technology. Without the use of pesticides we could not have met global food demands for the past 50 years. Before pesticide introduction rice yields were down by 57% and corn was down 32% (Knutson, 1999). Insect-protected corn allows American farmers to increase their yields between 5 and 20% (Gallivan, 1999). With GMO seeds, anyone who can plant a seed can have insect protection. This widens the domain of potential growers to include the illiterate and those in developing countries that may or may not have the capacity to understand complicated insecticide instructions.

There is an economic advantage to farmers using GMO grain. Enhanced seeds carry built in protection. This technology minimizes or completely eliminates the cost of fuel and labor for repeated application of powder and spray forms of insecticide. In Europe, up to $1 billion in lost yields was saved from the European corn borer by using GMO corn (Gallivan, 1999).

A three-year study in North Carolina found that, on average, Bt. fields used insecticides 0.7 times while conventional fields used them 2.7 times (Knutson, 1999). In 1998, the National Agriculture Statistics Service reported that 2 million fewer pounds of insecticide were used to control bollworm and budworm than in 1995, before Bt. cotton was introduced (Knutson, 1999). These numbers seem quite convincing.

There are also health advantages to genetically enhanced crops. Bt. corn has less bug damage to the ear, which means there are fewer mycotoxins, which pose a human health risk (Hein, 1999). Bt. corn nutrient levels-fats, proteins, carbohydrates, vitamins, and minerals-remain the same as non-biotech products. And the levels of toxins and allergens are often lower than conventional grain (Novartis, 1999). Additionally, genetically enhanced food can be engineered to contain higher nutrient levels, taste better, and be healthier at a lower cost (American...1999). There are currently corn and soybeans that will produce cooking oil that is lower in saturated fats (Hein, 1999). Finally, 400 million people worldwide suffer from vitamin A deficiency. Additionally, iron deficiency is common in people with rice based diets-nearly 4 billion which is 2/3 of the world population. There is now genetically engineered rice that is enriched with beta-carotene (a vitamin A precursor) and extra iron (American...1999). This new golden rice offers improved nutrition for billions whose staple food is rice in developing countries.

Problems

Unfortunately, there are also problems with GMO grain. Critics of biotechnology claim that science is not advanced enough to guarantee the safety of the new bioengineered food. "We don't know what the products will prove to be in the long run. To say we know is an expression of faith, not knowledge," says Mark Silbergeld, representative of the Consumers Union.

Three agencies regulate GMO crops ad Foods: the Environmental Protection Agency (EPA), the Food and Drug Administration (FDA), and the Agriculture Department (Brasher, 1999). "Our regulatory system is based on the most rigorous scientific information available, is credible, is defensible, and will serve to protect the environment and public health," says Jan Anderson, an official from the EPA (Novartis, 1999).

Novartis Seed, Inc. is a leading agriculture and biotechnology research organization that develops genetics and value-added products, and produces and sells corn, soybean, alfalfa, sunflower, sorghum, wheat, sugarbeet, vegetable, and flower seeds. They released the statement, "We know-and the most stringent review processes from government agencies around the world confirm-our products are safe for humans, animals, and non-target insects" (Gallivan, 1999). All Novartis seeds: NK brand Bt corn hybrid and Round Ready soybean varieties have received full regulatory clearance for all uses in the U.S. This process included reviews by the FDA, United States Department of Agriculture (USDA), and the EPA (Bernens, 1999). Novartis Bt corn products meet every environmental requirement set by the US government (Gallivan, 1999). Grain and Soybeans produced from NK Brand seeds have moved freely into commerce since their release in 1996 and 1997 (Novartis, 1999). All Novartis varieties have been approved for import into the European Union (E.U.) countries (Novartis, 1999). Thirty scientific committees worldwide have agreed Novartis seeds NK Brand Bt corn hybrids and Round Ready soybean varieties are as safe and wholesome as conventional products (Bernens, 1999). GMO grain and other plant material are approved exports to Canada, E.U., Japan, and several other countries without regard to identity preservation.

Biotech ingredients, primarily from corn and soybeans are used in everything from tortilla chips to soda and baby formula (Brasher, 1999). Does this take away the consumers right to choose? The consumers never really had the choice. Products containing GMO ingredients were never labeled in the United States. However, even if they were, what that means is debatable.

Identity Preservation is very difficult to establish do to cross-pollination. A GMO crop may cross-pollinate a conventional crop via insects or wind. Absolute Identity Preservation is nearly impossible due to physical and technical difficulties. There may be residues of GMO grain or beans in machinery, storage bins, augers, or trucks that will mix with conventional crops (Bernens, 1999). Threshold standards for biotech traits have not yet been established for non-GMO products (Bernens, 1999). If a farmer is selling to a non-GMO market, they must establish a pure identity. To establish identity, one must have precise field maps and records certifying which variety of seed produced grain and variety bred using conventional techniques and a strict isolation protocol.

Another disadvantage is a technology that Monsanto, a huge, international seed company, is incorporating into their seeds. This technology has been dubbed-Terminator technology. This technology was invented in cooperation with USDA researchers (www.new). It works by attaching a promoter from a gene called Late Embryogenesis Abundant (LEA) to a gene that stops germination and then inserting this gene into a seed. When the seed grows into a plant, the promoter triggers the terminator gene, thus sterilizing the plants maturing seeds (www.new). This doesn't allow people to keep seeds from their last crop to plant the next year.

1.4 billion people worldwide depend on keeping their own seeds for next the year's crop (www.ft/comm). In fact, 15-20% of the world's food is grown by farmers who cannot afford to buy seeds every year (www.gaia). Closer to home, 20-30% of all soybeans fields in the US Midwest are planted with farm-saved seed (www.gaia).

The argument then arises that if the farmer wants to keep his seeds, then he can choose to use a different brand of seeds. This is not entirely correct. Farmers who don't purchase Monsanto seeds with the terminator technology may find their saved seeds sterile. Terminator genes may be transferred by pollen, which may cause mutations that could spread to other plants, including surrounding wild plants (www.ft/comm). Additionally, seed companies, national governments, and banks offer credit only to those farmers who agree to plant selected varieties (www.gaia). These varieties may include those with terminator technology.

Many people have become outraged by the existence of this technology. "The terminator technology is a recipe for exacerbating and greatly increasing the problem of world hunger," -LoriAnn Thrupp, Director of Sustainable Agriculture at the World Resources Institute (www.gaia). "The sole purpose is to facilitate monopoly control, and the sole beneficiary is agribusiness," -Camila Montecinos of Chile's Center for Education and Technology (www.gaia).

One fact that contributes to the outrage is the fact that public funds were used to develop terminator technology that has no agronomic benefit to farmers and no benefit to consumers. (This technology was developed, in part, by the USDA.)

In their own defense, Monsanto says that the "Terminator's enormous profitability will motivate seed companies to intensify research and the whole world will benefit" (www.gaia). But, the seed industry has never developed seeds adapted to the needs of small and substance farmers on marginal lands who will be affected the most by this technology. The USDA argues that the technique will benefit poor farmers because it will let companies protect their intellectual property while marketing a wider variety of genetically engineered seeds to suit many growing conditions (www.new). Melvin Oliver, an USDA molecular biologist and primary inventor of the technology said, "My main interest is protection of American technology. Our mission is to protect US agriculture, and to make us competitive in the face of foreign competition. Without this, there is no way of protecting the technology [patented seed]." So the USDA admits that its goal is to "increase the value of proprietary seed owned by US seed companies and to open up new markets in second and third world countries" (www.gaia). However, is it ethical to profit so profusely from these markets? It seems to me that this is another case of the rich getting richer and the poor getting poorer. But how does the general public feel about GMO crops?


Societal Views


In a study conducted by the Wirthlin Group which was commissioned by the International Food Information Council, they found that 1 in 3 Americans admits to knowing little to nothing about biotechnology (Minnichsoffer, 1999). This lays great responsibility on the media to get out accurate information. So has the media risen to the challenge?

The University of Arizona did a study that suggested that there was the potential for bollworms to develop a resistance to genetically modified cotton. Cornell University did a study suggesting GM corn could wipe out the Monarch butterfly. Both studies were summarized in Nature. Both led one to believe Science had made oversights in reviewing the potential risks of biotechnology (Foster, 1999). However, upon peer review, these articles didn't fair so well. Reviewers pointed out problems with these studies. For example, the Monarch butterfly study had not been done in a field environment (Gallivan, 1999). So how do these "questionable" articles get into scientific journals?

"Journals, seeking to make a name for themselves, want to publish the little studies because they are interesting. And research authors get around the fact that the studies are misleading with wiggle words like 'this is only a laboratory study and it makes no conclusions about what would happen in a natural environment'" (Foster, 1999).

Professor Mick Crawley had this response to the bollworm article: "these little studies are interesting because they show the things that could happen, but they don't resolve the problems because they don't consider the effect over the whole life cycle (of the insect)…What people are doing with these little snippets are fanning the flames" (Foster, 1999).

Is this their motive for publishing these types of articles? John Foster, professor at the University of Nebraska, believes so. "Some scientists don't accept the general consensus of the safety of GMO grain by the Scientific community and are willing to use questionable methods to take their case to the front line…The quickest way to get attention is to conduct a laboratory study knowing what the outcome will be and then find accomplices to make a big deal out of it" (Foster, 1999).

These types of articles have contributed to much confusion in the general public and allowing people to forget that the USDA, FDA, and EPA have tested GMO products for at least a decade (Hein, 1999). Novartis' Bt corn in particular has been tested not only by these three government agencies, but also by thirty scientific communities around the world and all have concluded Bt. corn is as safe as conventional corn (American...1999). However, these types of reassurances have not quieted activist groups such as Green Peace. There are some Scientists that have some things to say about that as well.

"The activists are using the same types of tactics that they have used for years in opposition to chemical pesticides. Now, when scientists have developed a non-chemical control by inserting a single gene into a plant, the activists oppose that" (Knutson, 1999). A prime example of this is Bt. corn. Again, Bt stands for Bacillus thuringiensis-a bacteria. This bacterium has been used in spray and powder form for years. Chemical pesticide opponents have endorsed these sprays and powders because they are effective against target insects and harmless to birds, mammals, and beneficial insects (Knutson, 1999). But now that a way has been developed that has eliminated the need to apply the powder or spray, there is much opposition.

"[Activists]. . .want to minimize the potential risks associated with the use of pesticides… I am puzzled when the same people oppose a technology that would accomplish this very goal. They obviously do not know what it takes to produce a crop on a large scale" (Knutson, 1999).

This mass suspicion also exists in Europe. The European public is crying out for labeling of any food that contains GMO crops despite the reassurances of their regulatory government agencies. However, there may be some validity for their mistrust, which seems to stem from the recent health issues in Europe such as mad cow disease and dioxin poisoning, not necessarily the GMO grain itself (Hein, 1999).

There are companies who have responded to this scare and are taking a non-GMO policy. It is not terribly difficult to find various lists of these companies on the Internet. One such company is Gerber. What makes this interesting is that Gerber and Novartis are owned by the same company. Gerber decided to reduce their use of genetically enhanced ingredients in its baby-foods. However, they released the statement that this was done not because of safety concerns, rather consumer preferences stating that parents with young children are often very selective of foods they feed their babies (American...1999).

GMO grain companies are fighting back. Novartis Seeds and Novartis Crop Protection started a public education and awareness program. It has done this because "The Company believes that openness will play an important role in the acceptance of biotechnology, and is committed to providing complete and accurate information about its products."-Jack T. Bernens, company official (Bernens, 1999).

So what exactly is Novartis doing? Novartis has worked in conjunction with the Chicago Museum of Science and Industry to open a 4000 square foot exhibit. This exhibit will educate people on modern food production and how the use of technology improves the quality and quantity of food and fiber. Novartis has invested $300,000 in this project (Shonsey, 1999). Novartis also helps fund Your World an educational magazine that is distributed to middle schools and high schools for use in their Science classes. Novartis has invested $150, 000 for the purposes of educating children in the area of biotechnology (Shonsey, 1999).

Novartis is not trying to eliminate all other methods of farming, but rather to gain acceptance of their farming technology. Novartis realizes that there is a separate market for conventional and organically grown food. "Some producers-in the US and Abroad-may be willing to pay for the added cost of producing crops developed without the use of agricultural biotechnology. And that may open new markets for some producers. But for most farmers, biotechnology is critical to their future success in producing the world's most affordable high quality food."-Ed Shonsey, President and CEO of Novartis (Shonsey, 1999).


Conclusion


GMO grain offers many benefits and a few drawbacks. It seems to me that the current benefits far outweigh the drawbacks. However, it is important to consider both these aspects carefully. Ultimately, we don't know what the future overall health outcome will be for humans or animals. However, there is no concrete reason to believe that GMO grain will be any worse for our bodies than conventionally grown grain. In fact, GMO grain has the potential to be healthier for us due to decreased pesticide use and it's ability to make the grain healthier. I believe that further education of the general public is required and that the press needs to assume more responsibility for the accurate reporting of current facts. Perhaps Ronald Krutson, professor of agriculture economics at Texas A&M and director of the Agriculture and Food Policy Center sums it up best, "Such a technology deserves to be embraced-if not with open arms, at least with an open mind" (Knutson, 1999).

 


Works Cited

American Council on Science and Health. "Biotechnology Makes Rice Even More Healthful." Sept. 7, 1999.

Beeler, Amy. News Release, "European Union Finalizes Approval of NK Brand Yieldgard Hybrids." June 11, 1998.

Bernens, Jack. Novartis Seeds Company Letter. Oct. 4, 1999.

Brasher, Philip. Associated Press, "Biotech Crops, Foods receive EPA's support." Oct. 8, 1999.

Foster, John E. The Washington Times, "Butterflies Bearing Grenades." Sept. 20, 1999.

Gallivan, Karen Park. Novartis Company Letter. May 19, 1999.

Hein, Pam and Weinzierl, Kathy. The Pentograph, "Do American Consumers Accept Genetically Altered Foods?" Sept. 27, 1999.

Knutson, Ronald. Omaha.com. "Genetic Crops Protect Environment." Sept. 15, 1999.

Minnichsoffer, Tony. Novartis Media Release, "Novartis Commits $450,000 to Public Science Education to Expand Ag Biotech Awareness." Sept. 1999.

Novartis Seed Publication. "Biotechnology Talk Points." Oct. 1999.

Shonsey, Ed. Novartis Company Letter. Sept. 1999.

Web Resources

www.tt/comm.com/ensign/terminator/terminator.html available: Nov. 4, 1999.

Edwards, Rob. "Devilish seed" [Archive:Oct. 10, 1998]. available: Nov. 4, 1999. www.newscientist.com/ns/981010/nseed.html

" 'Terminator' Technology Threatens World Food Security." March 1999. available: Nov. 4, 1999. www.gaiabooks.co.uk/environment/terminatorseed.html