Organic Syntheses for Enzyme Research

Enzymology research sometimes requires substrates or analogs that can not be purchased from chemical suppliers.  GC students are participating in research to synthesize the following two compounds which will be used in collaboration with another laboratory performing research in pyridoxal phosphate-dependent enzymes at the Sapienza University of Rome, Italy.

 

Synthesis of N-(5’-phospho-4’-pyridoxyl)-L-serine

 

 

 

Synthesis of ß-hydroxy-ε-N-trimethyl-L-lysine