Lecture Topics/Genetics Home Page

I. Transcriptional control

A. Operon model

1. What is the operon model?

2. Example of an inducible system: lac operon

3. Example of catabolite repression: lac operon

4. Example of a repressible system: trp operon

5. Example of an attenuator-controlled system: trp operon

B. Transposable elements (mobile genetic elements)

1. Insertion sequences (IS elements)

2. Composite transposon

3. Movement of transposon

4. Effect of composite transposon on bacteria--an example

C. Heat shock proteins

D. Differences in promoter efficiency

II. Translational control

A. Order (position) of gene in the operon affects rate of translation

B. Antisense RNA inhibits translation

C. Binding of mRNA to ribosome (binding efficiency varies)

D. Codon preference

III. Post translational control of gene expression

A. Feedback inhibition

B. Protein degradation

IV. Questions you should be able to solve: chapter 13--1, 3, 5, 13, 23, 25, 26, 29, 31, 34, 35, 36