Gene expression in eukaryotes (chapter 15, pp 423-432, 437-446, cancer-449-461)

Lecture Topics/Genetics Home Page

I. Patterns of development and gene expression
A. Hierarchy of genes involved in establishing body plan
B. Gradient hypothesis
1. Example: determining anterior-posterior coordinates
2. Mutants are studied to understand the actions of certain genes
C. Homeotic genes
II. Gene rearrangement (DNA splicing; pp. 440-449)
A. Immunoglobulin genes
B. Rearrangements of genome explains diversity of antibodies
III. Methylation (pp. 437-438)
IV. Transposons (pp. 438-440): read on your own
V. Cancer